Creatinine what is it? Test Purpose and Effect on Kidneys

Creatinine what is it? Test Purpose and Effect on Kidneys

Its analysis helps to know the functioning of the kidneys;

Within the different parameters that are studied in a routine blood test, one of the most common and usual is known as serum creatinine, mainly because its analysis helps to know the functioning of the kidneys; rather, whether or not the kidneys are performing their functions correctly. But in a routine urine analysis, a parameter related to creatinine is also analyzed, although this time it is medically known as urine creatinine, explains the best nephrologist in Delhi.

What is creatinine?

Creatinine is a substance present in the blood that is produced by the degradation of creatine found in the muscles, it is a waste product that the kidneys filter in order to extract it from the blood and remove it through the urine. So when analyzing creatinine levels it is possible to identify if there is a problem in the kidneys, especially when its value is high in the bloodstream, since it can mean that the kidneys are not able to eliminate it and therefore it is accumulating in the organism, explains kidney specialist in Delhi.

It is generated by our muscles (both by its activity and by the muscle mass itself), and they produce it at a constant speed as part of our normal daily activity.

Since creatinine is a substance that is produced in the body depending on the level of muscle mass, it is normal for men to have higher blood creatinine levels than women, since they usually have more developed muscles.

What is your analysis for?

We must bear in mind that the kidneys are the organs responsible for filtering creatinine by excreting it through the urine, so its measurement is especially useful to monitor if the kidneys are performing their function correctly, explains the nephrologist in Delhi.

The creatinine test is a simple test that becomes the most common indicator about the person’s renal function, says the best kidney specialist in Delhi. For this reason, it is routinely included in the most basic and common blood tests, both in its serum form and in urine. And if renal function is abnormal, creatinine levels tend to increase in the blood since in fact a smaller amount of creatinine is eliminated in the urine.

Normal blood creatinine values

Creatinine values ​​may vary from one laboratory to another, since some laboratories usually analyze different samples, or use different measurements. However, the average normal values ​​are as follows:

  • Normal values ​​of serum creatinine in adult men:7-1.3 mg / dl.
  • Normal values ​​of serum creatinine in adult women:5-1.2 mg / dl.
  • Normal values ​​in children:2-1 mg / dl.

While values ​​above 4 mg / dl are considered as an indication of significant renal failure.

On the other hand, it is possible that when intense physical exercise has been practiced before performing the blood test, there will be slight increases in the blood creatinine value. This increase does not correspond to renal failure, but it reflects muscle activity, top kidney specialist in Delhi says.

Elevated blood creatinine levels may indicate the presence of:

  • Renal insufficiency.
  • Urinary tract obstruction.
  • Acute tubular necrosis
  • Dehydration
  • Diabetic Nephropathy
  • Glomerulonephritis
  • Muscular dystrophy.
  • Pyelonephritis
  • Reduction of renal blood flow.
  • Rhabdomyolysis

What can cause high creatinine?

When blood creatinine levels are above normal, they may indicate a lesion in the blood vessels of the kidneys, a kidney infection or a reduction in blood flow to the kidneys, for example. Some symptoms explained by kidney doctor in Delhi that may arise in cases of high creatinine are:

  • Excessive tiredness;
  • Swelling of the legs or arms;
  • Feeling short of breath;
  • Frequent confusion;
  • Nausea and vomiting

However, athletes and bodybuilders may also have high creatinine due to high muscle activity and not due to kidney injury, says the top nephrologist in Delhi.

Decreased serum creatinine values

Low blood creatinine values ​​are not a cause for concern, being more frequent in pregnant women and in patients with liver diseases, since the liver is also responsible to produce creatinine.

However, nephrologist in Delhi says that in some people it can also indicate diseases in the muscles such as muscular dystrophy, for example, which causes other symptoms such as weakness, muscle pain or difficulty moving the arms or legs.